Foreword
Research Structures
Energy, Environment, and Biodiversity
- Metallic Materials Engineering
- Solar Energy
- Biodiversity and Ecosystems in Fields and Forests of the Atlantic Forest
- Economic, Human, and Environmental Development
- Primatology
- Genetics, Evolution, Ecology, and Conservation of Carnivores
- Oleochemistry: Processes and Products
- Technologies to Mitigate Environmental Impacts
- Ichthyology
- Ornithology
- The Center for Wind Energy
Humanities and Ethics
- Fundamental Rights
- Theological and Ethical Anthropology
- The Political Authoritarianism and Press in Contemporary Brazil
- Christology within the Contemporary Latin American Context
- Law and Bioethics
- Clinical Bioethics
- Ecclesiology and Emergent Problems
- Analytic Epistemology
- Ethics, Contemporaneity, and Deconstruction: The Philosophical Criticism of Violence
- Immigration, Towns, and Foreigners Narratives of Brazil (1864–1964)
- Criminal Procedure and Democratic Rule of Law
Culture and Education
- Southern Writers Collection
- Architecture and Heritage
- Culture, Subjectivity, and Formative Policies
- Between the Memories and Stories of Schools at Rio Grande do Sul: From the Deutscher Hilfsverein to Farroupilha School (1858-2008)
- Enunciation and Discourse
- Education for Health and Inclusive Education
- Teaching of Physics
- Format Y: Formation in Mathematics for Generation Y
- History of Literature: The Investigation and Diffusion of Sources
- Reading Literature: The School and Other Social Agencies
- Chemical Education
- Relationship between the Nature of Science and Science Education
- Literature, History, and Theories on the Imaginary
- Training of Professors, Licentiates, and Pedagogical Practices
Society and Development
- Companies and Organizations
- Law and Economy
- Study and Research on Violence
- Family, Social Work, and Health
- Architecture and Industrialization
- Agribusiness
- Social Well-being Economics
- Applied Mathematics
- Class Action Lawsuits
- Psychology and Social Policies: Memory, History, and Production of the Present Time
- Inter-organizational Relationships and Systemic Competitiveness
- Parties, Elections, and Political Communication
- Fundamental Principles of Tax Law
- Social Demands and Policies
Information and Communication Technology
- Wireless, Wired, and Optic Communications
- Organizational Communication
- Strategy and Innovation
- Hardware Project Support
- Computing Molecular Biophysics – The Modeling and Simulation of Biosystems
- Technological Development in Telehealth
- Resource Management and Virtualization
- The Management and Governance of Information Technology
- International News at the Global Village
- Communication Science
- Ubiquity and Technological Convergences in Communication
- Aerospace Research
- The Performance Evaluation Group
- The Group on Systems, Signals, and Computing
Biology and Health
- Cancer and Other Pathologies of the Oral and Maxillofacial Region
- Memory
- Molecular and Functional Biology
- Cardiometabolic Risk, Aging, and Nutrition
- Health Education and Work
- Structural Biochemistry
- Pediatric Respirology
- Applied Pharmacology: Characterization of Mechanisms Involved in Pain, Inflammation and Cancer
- Immunology and Immunodiagnostics
- Nephrology
- Neurosciences
- Orthodontics
- The Promotion of Health in Longevity
- Olympic Studies and Health Sciences
- Nerve Regeneration
- Intensive Neonatal Medicine and Congenital Infections
- Aerospace Pharmacy
- Medical Imaging
- Pulmonology
- Orofacial Pain and Temporomandibular Disorders
- Metabolic Transformations of Purines of Biological Importance
- The Study of Parasitosis, Biochemical Parameters, and Hematological Parameters Associated with Aging
- Aerospace Science
- Bioethics and Ethics Applied to Animals
- Pharmacovigilance
- Evaluation and Intervention in the Life Cycle
- Surgery for Obesity and Metabolic Syndrome
- Modification of Lifestyle and Cardiovascular Risk
- Nanostructures and Nanoscopy
- Clinical and Experimental Neuropsychology
- Psychology of Occupational Health
- Memory and Neurodegeneration
- Epidemiology, Neurology, and Immunology
- Chemistry of Natural Products
- Health Economics
Research Structures and Researchers
- RESEARCH STRUCTURES AND RESEARCHERS
- Business School: Management, Accounting and Economics (FACE)
- School of Architecture and Urbanism (FAU)
- School of Biosciences (FABIO)
- School of Aeronautical Sciences (FACA)
- School of Social Communication (FAMECOS)
- Law School (FADIR)
- School of Education (FACED)
- School of Physical Education and Sport Science (FEFID)
- School of Nursing, Nutrition and Physiotherapy (FAENFI)
- School of Engineering (FENG)
- School of Pharmacy (FFARM)
- School of Philosophy and Human Sciences (FFCH)
- School of Physics (FAFIS)
- School of Computer Science (FACIN)
- School of Letters: Languages, Linguistics and Literature (FALE)
- School of Mathematics (FAMAT)
- School of Medicine (FAMED)
- School of Dentistry (FO)
- School of Psychology (FAPSI)
- School of Chemistry (FAQUI)
- School of Social Work (FSS)
- School of Theology (FATEO)
- Institute of Bioethics (IB)
- Institute of Geriatrics and Gerontology (IGG)
- Institute of Research and Development (IDÉIA)
- Institute of Biomedical Research (IPB)
- Institute of Toxicology and Pharmacology (INTOX)
- Institute of the Brain (InsCer)
- Institute of Environment and Natural Resources (IMA)
- Museum of Sciences and Technology (MCT)
The action of ATP and adenosine in the central nervous system
The mechanisms involved in seizures, stress, cognitive impairment, and neurodegenerative diseases have been the focus of the Research Group on Metabolic Transformations of Purines of Biological Importance. The researchers in this Group seek to understand the action of the molecules ATP and adenosine in the central nervous system and how the control of the levels of these molecules may be related to disease.
The Group, created in 1999, has been a pioneer in Brazil in the evaluation of the role of ATP and adenosine using zebrafish (Danio rerio), considered to be one of the most important models for biomedical studies. Enzymes able to modulate the levels of ATP and adenosine were identified in this experimental model. In addition, the potential of this enzymatic pathway as a target for the development of pharmaceutical agents and in the determination of neurotoxicity mechanisms has been evaluated.
Biochemical, molecular, and behavioral studies have generated national recognition for this research group, coordinated by Professor Carla Denise Bonan. The team has three faculty researchers and 20 undergraduate, graduate, and post-doctoral students, who have written more than 130 articles published in international journals.
The group was awarded by the Support Program for the Centers of Excellence (Pronex), with PUCRS (School of Pharmacy), UFRGS, and FURG, seeking to establish a Center of Excellence in neurochemistry and psychopharmacology in zebrafish. One of the results of this project was the organization of the first LAZEN Zebrafish Course at PUCRS, with support from the Latin American Network of Zebrafish Studies (LAZEN) and the participation of students and researchers from Brazil, Uruguay, Chile, Argentina, and Ecuador.
The next challenges involve the development of a new research group called ZebLab, which will join together the users of this experimental model, and the expansion of the infrastructure to maintain this model together with the Center for Experimental Biological Models of PUCRS.